Symbol: Name: ID: |
PALLD palladin, cytoskeletal associated protein GFS:6161 |
Gene name: | PALLD |
Chromosome: | 4q32.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0992, SIH002, CGI-151 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919583 | Rat Genome Database ID: | RGD:1359390 |
HGNC ID: | HGNC:17068 | RefSeq IDs: | NM_001166108 |
Entrez Gene ID: | 23022 | Ensembl Gene ID: | ENSG00000129116 |
VEGA IDs: | UniProt ID: | Q8WX93 | |
UCSC ID: | uc003iru.2 | OMIM ID: | 608092 |
Pubmed: | PMID10231032 PMID 10931874 | ||
CCDS IDs: | CCDSCCDS34098.1 |
Palladin is a protein that in humans is encoded by the PALLD gene.
This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
Function: Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci.
Products for PALLD gene
Catalog | Product Name | Application | Company |
GFS:E06161 | palladin, cytoskeletal associated protein; ELISA kit | ELISA | n/a |
GFS:A06161 | palladin, cytoskeletal associated protein; Anti | ANTIBODIES | n/a |
GFS:P06161 | palladin, cytoskeletal associated protein; Protien | Protien | n/a |