Symbol: Name: ID: |
OSBPL2 oxysterol binding protein-like 2 GFS:4910 |
Gene name: | OSBPL2 |
Chromosome: | 20q13.3 |
Previous Symbols: | |
Previous Names: | oxysterol-binding protein-like 2 |
Aliases: | KIAA0772, ORP-2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2442832 | Rat Genome Database ID: | RGD:1311312 |
HGNC ID: | HGNC:15761 | RefSeq IDs: | NM_014835 |
Entrez Gene ID: | 9885 | Ensembl Gene ID: | ENSG00000130703 |
VEGA IDs: | OTTHUMG00000032909 | UniProt ID: | Q9H1P3 |
UCSC ID: | uc002yck.1 | OMIM ID: | 606731 |
Pubmed: | PMID10588946 PMID 11861666 | ||
CCDS IDs: | CCDSCCDS13494.1 CCDS CCDS13495.1 |
Oxysterol-binding protein-related protein 2 is a protein that in humans is encoded by the OSBPL2 gene.
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Function: Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate.
Products for OSBPL2 gene
Catalog | Product Name | Application | Company |
GFS:E04910 | oxysterol binding protein-like 2; ELISA kit | ELISA | n/a |
GFS:A04910 | oxysterol binding protein-like 2; Anti | ANTIBODIES | n/a |
GFS:P04910 | oxysterol binding protein-like 2; Protien | Protien | n/a |