Noelin is a protein that in humans is encoded by the OLFM1 gene.

This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Seems to play an important role in regulating the production of neural crest cells by the neural tube (By similarity).