Symbol: Name: ID: |
NIN ninein (GSK3B interacting protein) GFS:4193 |
Gene name: | NIN |
Chromosome: | 14q21-q22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:105108 | Rat Genome Database ID: | RGD:1306492 |
HGNC ID: | HGNC:14906 | RefSeq IDs: | NM_016350 |
Entrez Gene ID: | 51199 | Ensembl Gene ID: | ENSG00000100503 |
VEGA IDs: | OTTHUMG00000029569 | UniProt ID: | Q8N4C6 |
UCSC ID: | uc001wyi.2 | OMIM ID: | 608684 |
Pubmed: | PMID11004522 PMID 11162463 | ||
CCDS IDs: | CCDSCCDS32078.1 CCDS CCDS32079.1 |
Ninein is a protein that in humans is encoded by the NIN gene.
This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008].
Function: Centrosomal protein required in the positioning and anchorage of the microtubule minus-end in epithelial cells. May also act as a centrosome maturation factor. May play a role in microtubule nucleation. Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules.
Products for NIN gene
Catalog | Product Name | Application | Company |
GFS:E04193 | ninein (GSK3B interacting protein); ELISA kit | ELISA | n/a |
GFS:A04193 | ninein (GSK3B interacting protein); Anti | ANTIBODIES | n/a |
GFS:P04193 | ninein (GSK3B interacting protein); Protien | Protien | n/a |