Symbol: Name: ID: |
NLN neurolysin (metallopeptidase M3 family) GFS:5183 |
Gene name: | NLN |
Chromosome: | 5q12.3 |
Previous Symbols: | AGTBP |
Previous Names: | angiotensin binding protein |
Aliases: | KIAA1226 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1923055 | Rat Genome Database ID: | RGD:621518 |
HGNC ID: | HGNC:16058 | RefSeq IDs: | NM_020726 |
Entrez Gene ID: | 57486 | Ensembl Gene ID: | ENSG00000123213 |
VEGA IDs: | OTTHUMG00000097803 | UniProt ID: | Q9BYT8 |
UCSC ID: | uc003juf.2 | OMIM ID: | 611530 |
Pubmed: | PMID10574462 | ||
CCDS IDs: | CCDSCCDS3989.1 |
Neurolysin, mitochondrial is a protein that in humans is encoded by the NLN gene.
This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.[provided by RefSeq, Jun 2010]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Function: Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity).
Products for NLN gene
Catalog | Product Name | Application | Company |
GFS:E05183 | neurolysin (metallopeptidase M3 family); ELISA kit | ELISA | n/a |
GFS:A05183 | neurolysin (metallopeptidase M3 family); Anti | ANTIBODIES | n/a |
GFS:P05183 | neurolysin (metallopeptidase M3 family); Protien | Protien | n/a |