Symbol: Name: ID: |
NCDN neurochondrin GFS:6570 |
Gene name: | NCDN |
Chromosome: | 1p34.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NCDN-1, NCDN-2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1347351 | Rat Genome Database ID: | RGD:621734 |
HGNC ID: | HGNC:17597 | RefSeq IDs: | NM_001014839 |
Entrez Gene ID: | 23154 | Ensembl Gene ID: | ENSG00000020129 |
VEGA IDs: | OTTHUMG00000059204 | UniProt ID: | Q9UBB6 |
UCSC ID: | uc001bza.2 | OMIM ID: | 608458 |
Pubmed: | PMID15007648 | ||
CCDS IDs: | CCDSCCDS392.1 CCDS CCDS30672.1 |
Neurochondrin (also known as its murine homologue, Norbin) is a protein that in humans is encoded by the NCDN gene.
This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Several alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jul 2008].
Function: Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling (By similarity). Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
Products for NCDN gene
Catalog | Product Name | Application | Company |
GFS:E06570 | neurochondrin; ELISA kit | ELISA | n/a |
GFS:A06570 | neurochondrin; Anti | ANTIBODIES | n/a |
GFS:P06570 | neurochondrin; Protien | Protien | n/a |