Symbol: Name: ID: |
MTPN myotrophin GFS:4837 |
Gene name: | MTPN |
Chromosome: | 7q33-q35 |
Previous Symbols: | |
Previous Names: | |
Aliases: | MYOTROPHIN, GCDP, V-1 |
Name Aliases: | granule cell differentiation protein |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:99445 | Rat Genome Database ID: | RGD:619806 |
HGNC ID: | HGNC:15667 | RefSeq IDs: | NM_145808 |
Entrez Gene ID: | 136319 | Ensembl Gene ID: | ENSG00000105887 |
VEGA IDs: | OTTHUMG00000155627 | UniProt ID: | P58546 |
UCSC ID: | uc003vte.3 | OMIM ID: | 606484 |
Pubmed: | PMID11474205 | ||
CCDS IDs: | CCDSCCDS5842.1 |
Myotrophin is a protein that in humans is encoded by the MTPN gene.
A bi-cistronic transcript encodes the products of both the myotrophin and leucine zipper protein 6 genes, which are located on chromosome 7. A cryptic ORF at the 3' end of the myotrophin transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Function: Potential role in cerebellar morphogenesis. May function in differentiation of cerebellar neurons, particularly of granule cells. Seems to be associated with cardiac hypertrophy.
Products for MTPN gene
Catalog | Product Name | Application | Company |
GFS:E04837 | myotrophin; ELISA kit | ELISA | n/a |
GFS:A04837 | myotrophin; Anti | ANTIBODIES | n/a |
GFS:P04837 | myotrophin; Protien | Protien | n/a |