Symbol: Name: ID: |
MYOCD myocardin GFS:5193 |
Gene name: | MYOCD |
Chromosome: | 17p11.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | MYCD |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2137495 | Rat Genome Database ID: | RGD:631347 |
HGNC ID: | HGNC:16067 | RefSeq IDs: | NM_001146312 |
Entrez Gene ID: | 93649 | Ensembl Gene ID: | ENSG00000141052 |
VEGA IDs: | OTTHUMG00000058767 | UniProt ID: | Q8IZQ8 |
UCSC ID: | uc002gnn.2 | OMIM ID: | 606127 |
Pubmed: | PMID11439182 PMID 12397177 | ||
CCDS IDs: | CCDSCCDS11163.1 |
Myocardin is a protein that in humans is encoded by the MYOCD gene.
This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].
Function: Transcriptional factor that uses the canonical single or multiple CArG boxes DNA sequence. Binds CArG boxes only in the presence of serum response factor (SRF). Acts as a cofactor of SRF and modulates SRF-target genes. Regulates the expression of a set of cardiac and smooth muscle-specific genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (By similarity).
Products for MYOCD gene
Catalog | Product Name | Application | Company |
GFS:E05193 | myocardin; ELISA kit | ELISA | n/a |
GFS:A05193 | myocardin; Anti | ANTIBODIES | n/a |
GFS:P05193 | myocardin; Protien | Protien | n/a |