Symbol: Name: ID: |
MUTED muted homolog (mouse) GFS:7406 |
Gene name: | MUTED |
Chromosome: | 6p25.1-p24.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | MU, dJ303A1.3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2178598 | Rat Genome Database ID: | RGD:1306846 |
HGNC ID: | HGNC:18561 | RefSeq IDs: | NM_001199322 |
Entrez Gene ID: | 63915 | Ensembl Gene ID: | ENSG00000188428 |
VEGA IDs: | OTTHUMG00000014220 | UniProt ID: | Q8TDH9 |
UCSC ID: | uc003mxy.2 | OMIM ID: | 607289 |
Pubmed: | PMID11912185 | ||
CCDS IDs: | CCDSCCDS4506.1 |
Protein Muted homolog is a protein that in humans is encoded by the MUTED gene.
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene. [provided by RefSeq, Dec 2010].
Function: The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking (By similarity).
Products for MUTED gene
Catalog | Product Name | Application | Company |
GFS:E07406 | muted homolog (mouse); ELISA kit | ELISA | n/a |
GFS:A07406 | muted homolog (mouse); Anti | ANTIBODIES | n/a |
GFS:P07406 | muted homolog (mouse); Protien | Protien | n/a |