| Symbol: Name: ID: |
MOAP1 modulator of apoptosis 1 GFS:5760 |
| Gene name: | MOAP1 |
| Chromosome: | 14q32 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | MAP-1, PNMA4 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1915555 | Rat Genome Database ID: | RGD:1307230 |
| HGNC ID: | HGNC:16658 | RefSeq IDs: | NM_022151 |
| Entrez Gene ID: | 64112 | Ensembl Gene ID: | ENSG00000165943 |
| VEGA IDs: | UniProt ID: | Q96BY2 | |
| UCSC ID: | uc001ybj.2 | OMIM ID: | 609485 |
| Pubmed: | PMID11060313 | ||
| CCDS IDs: | CCDSCCDS9908.1 | ||
Modulator of apoptosis 1 is a protein that in humans is encoded by the MOAP1 gene.
The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. [provided by RefSeq, Jul 2008].
Function: Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
Products for MOAP1 gene
| Catalog | Product Name | Application | Company |
| GFS:E05760 | modulator of apoptosis 1; ELISA kit | ELISA | n/a |
| GFS:A05760 | modulator of apoptosis 1; Anti | ANTIBODIES | n/a |
| GFS:P05760 | modulator of apoptosis 1; Protien | Protien | n/a |
