Symbol: Name: ID: |
MFN1 mitofusin 1 GFS:7133 |
Gene name: | MFN1 |
Chromosome: | 3q26.32 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FLJ20693 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1914664 | Rat Genome Database ID: | RGD:621460 |
HGNC ID: | HGNC:18262 | RefSeq IDs: | NM_033540 |
Entrez Gene ID: | 55669 | Ensembl Gene ID: | ENSG00000171109 |
VEGA IDs: | OTTHUMG00000157385 | UniProt ID: | Q8IWA4 |
UCSC ID: | uc003fjs.2 | OMIM ID: | 608506 |
Pubmed: | PMID8358434 PMID 11181170 | ||
CCDS IDs: | CCDSCCDS3228.1 |
Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene.
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
Products for MFN1 gene
Catalog | Product Name | Application | Company |
GFS:E07133 | mitofusin 1; ELISA kit | ELISA | n/a |
GFS:A07133 | mitofusin 1; Anti | ANTIBODIES | n/a |
GFS:P07133 | mitofusin 1; Protien | Protien | n/a |