Symbol: Name: ID: |
MRPL40 mitochondrial ribosomal protein L40 GFS:3817 |
Gene name: | MRPL40 |
Chromosome: | 22q11.2 |
Previous Symbols: | NLVCF |
Previous Names: | nuclear localization signal deleted in velocardiofacial syndrome |
Aliases: | MRP-L22 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1332635 | Rat Genome Database ID: | RGD:1565444 |
HGNC ID: | HGNC:14491 | RefSeq IDs: | NM_003776 |
Entrez Gene ID: | 64976 | Ensembl Gene ID: | ENSG00000185608 |
VEGA IDs: | OTTHUMG00000150136 | UniProt ID: | Q9NQ50 |
UCSC ID: | uc002zpg.2 | OMIM ID: | 605089 |
Pubmed: | PMID9790763 PMID 11543634 | ||
CCDS IDs: | CCDSCCDS13760.1 |
39S ribosomal protein L40, mitochondrial is a protein that in humans is encoded by the MRPL40 gene.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008].
Products for MRPL40 gene
Catalog | Product Name | Application | Company |
GFS:E03817 | mitochondrial ribosomal protein L40; ELISA kit | ELISA | n/a |
GFS:A03817 | mitochondrial ribosomal protein L40; Anti | ANTIBODIES | n/a |
GFS:P03817 | mitochondrial ribosomal protein L40; Protien | Protien | n/a |