Symbol: Name: ID: |
MRPL12 mitochondrial ribosomal protein L12 GFS:329 |
Gene name: | MRPL12 |
Chromosome: | 17q25 |
Previous Symbols: | RPML12 |
Previous Names: | |
Aliases: | MRPL7/L12, MRPL7 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1926273 | Rat Genome Database ID: | RGD:1588559 |
HGNC ID: | HGNC:10378 | RefSeq IDs: | NM_002949 |
Entrez Gene ID: | 6182 | Ensembl Gene ID: | ENSG00000183093 |
VEGA IDs: | UniProt ID: | P52815 | |
UCSC ID: | OMIM ID: | 602375 | |
Pubmed: | PMID8626705 PMID 9169145 | ||
CCDS IDs: | CCDSCCDS11785.1 |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. (provided by RefSeq)
Products for MRPL12 gene
Catalog | Product Name | Application | Company |
GFS:E00329 | mitochondrial ribosomal protein L12; ELISA kit | ELISA | n/a |
GFS:A00329 | mitochondrial ribosomal protein L12; Anti | ANTIBODIES | n/a |
GFS:P00329 | mitochondrial ribosomal protein L12; Protien | Protien | n/a |