| Symbol: Name: ID: |
MINK1 misshapen-like kinase 1 GFS:6552 |
| Gene name: | MINK1 |
| Chromosome: | 17p13.2 |
| Previous Symbols: | |
| Previous Names: | misshapen-like kinase 1 (zebrafish) |
| Aliases: | B55, MINK, ZC3, MAP4K6, YSK2 |
| Name Aliases: | misshapen/NIK-related kinase |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1355329 | Rat Genome Database ID: | RGD:1359135 |
| HGNC ID: | HGNC:17565 | RefSeq IDs: | NM_001024937 |
| Entrez Gene ID: | 50488 | Ensembl Gene ID: | ENSG00000141503 |
| VEGA IDs: | UniProt ID: | Q8N4C8 | |
| UCSC ID: | uc010vsl.1 | OMIM ID: | 609426 |
| Pubmed: | PMID10708748 PMID 12087176 | ||
| CCDS IDs: | CCDSCCDS45588.1 CCDS CCDS45589.1 CCDS CCDS45590.1 | ||
Misshapen-like kinase 1 is an enzyme that in humans is encoded by the MINK1 gene.
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
Function: Serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in the development of the brain (By similarity).
Products for MINK1 gene
| Catalog | Product Name | Application | Company |
| GFS:E06552 | misshapen-like kinase 1; ELISA kit | ELISA | n/a |
| GFS:A06552 | misshapen-like kinase 1; Anti | ANTIBODIES | n/a |
| GFS:P06552 | misshapen-like kinase 1; Protien | Protien | n/a |
