Symbol: Name: ID: |
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) GFS:7513 |
Gene name: | MPP5 |
Chromosome: | 14q23.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | PALS1, FLJ12615 |
Name Aliases: | stardust |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1927339 | Rat Genome Database ID: | RGD:1308071 |
HGNC ID: | HGNC:18669 | RefSeq IDs: | NM_022474 |
Entrez Gene ID: | 64398 | Ensembl Gene ID: | ENSG00000072415 |
VEGA IDs: | UniProt ID: | Q8N3R9 | |
UCSC ID: | uc001xjc.2 | OMIM ID: | 606958 |
Pubmed: | PMID11927608 | ||
CCDS IDs: | CCDSCCDS9779.1 |
MAGUK p55 subfamily member 5 is a protein that in humans is encoded by the MPP5 gene.
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains (Tseng et al., 2001 [PubMed 11311936]). MPP5 is a member of the p55-like MAGUK subfamily.[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity).
Products for MPP5 gene
Catalog | Product Name | Application | Company |
GFS:E07513 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); ELISA kit | ELISA | n/a |
GFS:A07513 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); Anti | ANTIBODIES | n/a |
GFS:P07513 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); Protien | Protien | n/a |