Symbol: Name: ID: |
MMEL1 membrane metallo-endopeptidase-like 1 GFS:3952 |
Gene name: | MMEL1 |
Chromosome: | 1p36 |
Previous Symbols: | MMEL2 |
Previous Names: | membrane metallo-endopeptidase-like 2 |
Aliases: | SEP, NL1, NL2, NEPII |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1351603 | Rat Genome Database ID: | RGD:1309299 |
HGNC ID: | HGNC:14668 | RefSeq IDs: | NM_033467 |
Entrez Gene ID: | 79258 | Ensembl Gene ID: | ENSG00000142606 |
VEGA IDs: | OTTHUMG00000000846 | UniProt ID: | Q495T6 |
UCSC ID: | uc001ajy.2 | OMIM ID: | |
Pubmed: | |||
CCDS IDs: | CCDSCCDS30569.1 |
The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificiy with MME and cleaves peptides at the same amide bond (By similarity).
Products for MMEL1 gene
Catalog | Product Name | Application | Company |
GFS:E03952 | membrane metallo-endopeptidase-like 1; ELISA kit | ELISA | n/a |
GFS:A03952 | membrane metallo-endopeptidase-like 1; Anti | ANTIBODIES | n/a |
GFS:P03952 | membrane metallo-endopeptidase-like 1; Protien | Protien | n/a |