Symbol: Name: ID: |
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) GFS:3174 |
Gene name: | MAL2 |
Chromosome: | 8q23 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | MAL proteolipid protein 2 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2146021 | Rat Genome Database ID: | RGD:735066 |
HGNC ID: | HGNC:13634 | RefSeq IDs: | NM_052886 |
Entrez Gene ID: | 114569 | Ensembl Gene ID: | ENSG00000147676 |
VEGA IDs: | UniProt ID: | Q969L2 | |
UCSC ID: | uc003yop.2 | OMIM ID: | 609684 |
Pubmed: | PMID11549320 | ||
CCDS IDs: |
Protein MAL2 is a protein that in humans is encoded by the MAL2 gene.
This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway.
Products for MAL2 gene
Catalog | Product Name | Application | Company |
GFS:E03174 | mal, T-cell differentiation protein 2 (gene/pseudogene); ELISA kit | ELISA | n/a |
GFS:A03174 | mal, T-cell differentiation protein 2 (gene/pseudogene); Anti | ANTIBODIES | n/a |
GFS:P03174 | mal, T-cell differentiation protein 2 (gene/pseudogene); Protien | Protien | n/a |