Symbol: Name: ID: |
LOXL4 lysyl oxidase-like 4 GFS:6258 |
Gene name: | LOXL4 |
Chromosome: | 10q24 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FLJ21889, LOXC |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1914823 | Rat Genome Database ID: | RGD:1308588 |
HGNC ID: | HGNC:17171 | RefSeq IDs: | NM_032211 |
Entrez Gene ID: | 84171 | Ensembl Gene ID: | ENSG00000138131 |
VEGA IDs: | OTTHUMG00000018874 | UniProt ID: | Q96JB6 |
UCSC ID: | uc001kpa.1 | OMIM ID: | 607318 |
Pubmed: | PMID11292829 | ||
CCDS IDs: | CCDSCCDS7473.1 |
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May modulate the formation of a collagenous extracellular matrix.
Products for LOXL4 gene
Catalog | Product Name | Application | Company |
GFS:E06258 | lysyl oxidase-like 4; ELISA kit | ELISA | n/a |
GFS:A06258 | lysyl oxidase-like 4; Anti | ANTIBODIES | n/a |
GFS:P06258 | lysyl oxidase-like 4; Protien | Protien | n/a |