Symbol: Name: ID: |
LIPI lipase, member I GFS:7643 |
Gene name: | LIPI |
Chromosome: | 21q11.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | PRED5, LPDL, CT17 |
Name Aliases: | membrane-associated phospholipase A1 beta, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2443868 | Rat Genome Database ID: | RGD:1310162 |
HGNC ID: | HGNC:18821 | RefSeq IDs: | NM_198996 |
Entrez Gene ID: | 149998 | Ensembl Gene ID: | ENSG00000188992 |
VEGA IDs: | OTTHUMG00000074258 | UniProt ID: | Q6XZB0 |
UCSC ID: | uc002yjm.2 | OMIM ID: | 609252 |
Pubmed: | PMID12719377 | ||
CCDS IDs: | CCDSCCDS13564.1 |
The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. The encoded protein, which can be inhibited by sodium vanadate, may be found exclusively in sperm. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia. [provided by RefSeq, Jun 2010].
Function: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).
Products for LIPI gene
Catalog | Product Name | Application | Company |
GFS:E07643 | lipase, member I; ELISA kit | ELISA | n/a |
GFS:A07643 | lipase, member I; Anti | ANTIBODIES | n/a |
GFS:P07643 | lipase, member I; Protien | Protien | n/a |