Symbol: Name: ID: |
LIPH lipase, member H GFS:7329 |
Gene name: | LIPH |
Chromosome: | 3q27 |
Previous Symbols: | |
Previous Names: | |
Aliases: | mPA-PLA1, PLA1B |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2388029 | Rat Genome Database ID: | RGD:1592849 |
HGNC ID: | HGNC:18483 | RefSeq IDs: | NM_139248 |
Entrez Gene ID: | 200879 | Ensembl Gene ID: | ENSG00000163898 |
VEGA IDs: | OTTHUMG00000156657 | UniProt ID: | Q8WWY8 |
UCSC ID: | uc003fpm.2 | OMIM ID: | 607365 |
Pubmed: | PMID12213196 PMID 12063250 | ||
CCDS IDs: | CCDSCCDS3272.1 |
Lipase member H is an enzyme that in humans is encoded by the LIPH gene.
This gene encodes a membrane-bound member of the mammalian triglyceride lipase family. It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).
Products for LIPH gene
Catalog | Product Name | Application | Company |
GFS:E07329 | lipase, member H; ELISA kit | ELISA | n/a |
GFS:A07329 | lipase, member H; Anti | ANTIBODIES | n/a |
GFS:P07329 | lipase, member H; Protien | Protien | n/a |