Symbol: Name: ID: |
LMBR1 limb region 1 homolog (mouse) GFS:2895 |
Gene name: | LMBR1 |
Chromosome: | 7q36 |
Previous Symbols: | C7orf2 |
Previous Names: | chromosome 7 open reading frame 2 |
Aliases: | ACHP, FLJ11665 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1861746 | Rat Genome Database ID: | RGD:1563910 |
HGNC ID: | HGNC:13243 | RefSeq IDs: | NM_022458 |
Entrez Gene ID: | 64327 | Ensembl Gene ID: | ENSG00000105983 |
VEGA IDs: | OTTHUMG00000151510 | UniProt ID: | Q8WVP7 |
UCSC ID: | uc003wmw.3 | OMIM ID: | 605522 |
Pubmed: | PMID10329000 PMID 11090342 | ||
CCDS IDs: | CCDSCCDS5945.1 |
Limb region 1 protein homolog is a protein that in humans is encoded by the LMBR1 gene.
This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Putative membrane receptor.
Products for LMBR1 gene
Catalog | Product Name | Application | Company |
GFS:E02895 | limb region 1 homolog (mouse); ELISA kit | ELISA | n/a |
GFS:A02895 | limb region 1 homolog (mouse); Anti | ANTIBODIES | n/a |
GFS:P02895 | limb region 1 homolog (mouse); Protien | Protien | n/a |