Symbol: Name: ID: |
LPXN leupaxin GFS:3488 |
Gene name: | LPXN |
Chromosome: | 11 |
Previous Symbols: | |
Previous Names: | |
Aliases: | LDPL |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2147677 | Rat Genome Database ID: | RGD:1304981 |
HGNC ID: | HGNC:14061 | RefSeq IDs: | NM_001143995 |
Entrez Gene ID: | 9404 | Ensembl Gene ID: | ENSG00000110031 |
VEGA IDs: | UniProt ID: | O60711 | |
UCSC ID: | uc001nmw.2 | OMIM ID: | 605390 |
Pubmed: | PMID9565592 | ||
CCDS IDs: | CCDSCCDS7969.1 |
Leupaxin is a protein that in humans is encoded by the LPXN gene.
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009].
Function: Associates with PYK2 in lymphoid cells. May regulate signaling at sites of adhesion.
Products for LPXN gene
Catalog | Product Name | Application | Company |
GFS:E03488 | leupaxin; ELISA kit | ELISA | n/a |
GFS:A03488 | leupaxin; Anti | ANTIBODIES | n/a |
GFS:P03488 | leupaxin; Protien | Protien | n/a |