Symbol: Name: ID: |
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 GFS:5431 |
Gene name: | LILRA5 |
Chromosome: | 19q13.4 |
Previous Symbols: | LILRB7 |
Previous Names: | |
Aliases: | ILT11, LIR9, CD85, CD85f |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3647196 | Rat Genome Database ID: | RGD:1582781 |
HGNC ID: | HGNC:16309 | RefSeq IDs: | NM_021250 |
Entrez Gene ID: | 353514 | Ensembl Gene ID: | ENSG00000187116 |
VEGA IDs: | OTTHUMG00000065357 | UniProt ID: | A6NI73 |
UCSC ID: | uc002qfe.2 | OMIM ID: | 606047 |
Pubmed: | PMID10941842 | ||
CCDS IDs: | CCDSCCDS12888.1 CCDS CCDS12889.1 CCDS CCDS46177.1 CCDS CCDS46178.1 |
The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
Function: May plays a role in triggering innate immune responses. Seems not play a role for any class I MHC antigens recognition.
Products for LILRA5 gene
Catalog | Product Name | Application | Company |
GFS:E05431 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5; ELISA kit | ELISA | n/a |
GFS:A05431 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5; Anti | ANTIBODIES | n/a |
GFS:P05431 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5; Protien | Protien | n/a |