| Symbol: Name: ID: |
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 GFS:6439 |
| Gene name: | LRIG1 |
| Chromosome: | 3p14 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | LIG-1, DKFZP586O1624, LIG1 |
| Name Aliases: | ortholog of mouse integral membrane glycoprotein LIG-1, |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:107935 | Rat Genome Database ID: | RGD:1306788 |
| HGNC ID: | HGNC:17360 | RefSeq IDs: | NM_015541 |
| Entrez Gene ID: | 26018 | Ensembl Gene ID: | ENSG00000144749 |
| VEGA IDs: | OTTHUMG00000158727 | UniProt ID: | Q96JA1 |
| UCSC ID: | uc003dmx.2 | OMIM ID: | 608868 |
| Pubmed: | PMID11414704 PMID 12234026 | ||
| CCDS IDs: | CCDSCCDS33783.1 | ||
Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene. It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR-family, MET and RET.
Function: Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Products for LRIG1 gene
| Catalog | Product Name | Application | Company |
| GFS:E06439 | leucine-rich repeats and immunoglobulin-like domains 1; ELISA kit | ELISA | n/a |
| GFS:A06439 | leucine-rich repeats and immunoglobulin-like domains 1; Anti | ANTIBODIES | n/a |
| GFS:P06439 | leucine-rich repeats and immunoglobulin-like domains 1; Protien | Protien | n/a |
