| Symbol: Name: ID: |
KLB klotho beta GFS:4733 |
| Gene name: | KLB |
| Chromosome: | 4p14 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1932466 | Rat Genome Database ID: | |
| HGNC ID: | HGNC:15527 | RefSeq IDs: | NM_175737 |
| Entrez Gene ID: | 152831 | Ensembl Gene ID: | ENSG00000134962 |
| VEGA IDs: | OTTHUMG00000128577 | UniProt ID: | Q86Z14 |
| UCSC ID: | uc003gua.2 | OMIM ID: | 611135 |
| Pubmed: | |||
| CCDS IDs: | CCDSCCDS3451.1 | ||
Function: Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).
Products for KLB gene
| Catalog | Product Name | Application | Company |
| GFS:E04733 | klotho beta; ELISA kit | ELISA | n/a |
| GFS:A04733 | klotho beta; Anti | ANTIBODIES | n/a |
| GFS:P04733 | klotho beta; Protien | Protien | n/a |
