Symbol: Name: ID: |
KNTC1 kinetochore associated 1 GFS:6335 |
Gene name: | KNTC1 |
Chromosome: | 12q24.31 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0166, ROD |
Name Aliases: | rough deal homolog (Drosophila) |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2673709 | Rat Genome Database ID: | |
HGNC ID: | HGNC:17255 | RefSeq IDs: | NM_014708 |
Entrez Gene ID: | 9735 | Ensembl Gene ID: | ENSG00000184445 |
VEGA IDs: | UniProt ID: | P50748 | |
UCSC ID: | uc001ucv.2 | OMIM ID: | 607363 |
Pubmed: | PMID11146660 PMID 11590237 | ||
CCDS IDs: | CCDSCCDS45002.1 |
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein. [provided by RefSeq, Jul 2008]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.
Function: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.
Products for KNTC1 gene
Catalog | Product Name | Application | Company |
GFS:E06335 | kinetochore associated 1; ELISA kit | ELISA | n/a |
GFS:A06335 | kinetochore associated 1; Anti | ANTIBODIES | n/a |
GFS:P06335 | kinetochore associated 1; Protien | Protien | n/a |