Symbol: Name: ID: |
JPH1 junctophilin 1 GFS:3583 |
Gene name: | JPH1 |
Chromosome: | 8q21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | JP-1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1891495 | Rat Genome Database ID: | RGD:1308789 |
HGNC ID: | HGNC:14201 | RefSeq IDs: | NM_020647 |
Entrez Gene ID: | 56704 | Ensembl Gene ID: | ENSG00000104369 |
VEGA IDs: | UniProt ID: | Q9HDC5 | |
UCSC ID: | uc003yae.2 | OMIM ID: | 605266 |
Pubmed: | PMID10891348 PMID 10949023 | ||
CCDS IDs: | CCDSCCDS6217.1 |
Junctophilin-1 is a protein that in humans is encoded by the JPH1 gene.
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. [provided by RefSeq, Jul 2008].
Function: Contributes to the stabilization of the junctional membrane complexes, which are common to excitable cells and mediate cross-talk between cell surface and intracellular ion channels. Probably acts by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum. Contributes to the construction of skeletal muscle triad junctions (By similarity).
Products for JPH1 gene
Catalog | Product Name | Application | Company |
GFS:E03583 | junctophilin 1; ELISA kit | ELISA | n/a |
GFS:A03583 | junctophilin 1; Anti | ANTIBODIES | n/a |
GFS:P03583 | junctophilin 1; Protien | Protien | n/a |