Symbol: Name: ID: |
JAM2 junctional adhesion molecule 2 GFS:3968 |
Gene name: | JAM2 |
Chromosome: | 21q21.2 |
Previous Symbols: | C21orf43 |
Previous Names: | |
Aliases: | VE-JAM, JAM-B, JAMB, CD322 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1933820 | Rat Genome Database ID: | RGD:1561692 |
HGNC ID: | HGNC:14686 | RefSeq IDs: | NM_021219 |
Entrez Gene ID: | 58494 | Ensembl Gene ID: | ENSG00000154721 |
VEGA IDs: | OTTHUMG00000078441 | UniProt ID: | P57087 |
UCSC ID: | uc002ylp.1 | OMIM ID: | 606870 |
Pubmed: | PMID10779521 PMID 10945976 | ||
CCDS IDs: | CCDSCCDS42911.1 |
Junctional adhesion molecule B is a protein that in humans is encoded by the JAM2 gene. JAM2 has also been designated as CD322 (cluster of differentiation 322).
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May play a role in the processes of lymphocyte homing to secondary lymphoid organs.
Products for JAM2 gene
Catalog | Product Name | Application | Company |
GFS:E03968 | junctional adhesion molecule 2; ELISA kit | ELISA | n/a |
GFS:A03968 | junctional adhesion molecule 2; Anti | ANTIBODIES | n/a |
GFS:P03968 | junctional adhesion molecule 2; Protien | Protien | n/a |