| Symbol: Name: ID: |
INPP5F inositol polyphosphate-5-phosphatase F GFS:6147 |
| Gene name: | INPP5F |
| Chromosome: | 10q26.13 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | SAC2, KIAA0966, hSac2 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2141867 | Rat Genome Database ID: | RGD:1305777 |
| HGNC ID: | HGNC:17054 | RefSeq IDs: | NM_014937 |
| Entrez Gene ID: | 22876 | Ensembl Gene ID: | ENSG00000198825 |
| VEGA IDs: | OTTHUMG00000019158 | UniProt ID: | Q9Y2H2 |
| UCSC ID: | uc001leo.2 | OMIM ID: | 609389 |
| Pubmed: | PMID10231032 PMID 11274189 | ||
| CCDS IDs: | CCDSCCDS7616.1 | ||
The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
Function: Inositol 5-phosphatase which acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Hydrolyzes phosphatidylinositol 4,5-bisphosphate most effectively. Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation.
Products for INPP5F gene
| Catalog | Product Name | Application | Company |
| GFS:E06147 | inositol polyphosphate-5-phosphatase F; ELISA kit | ELISA | n/a |
| GFS:A06147 | inositol polyphosphate-5-phosphatase F; Anti | ANTIBODIES | n/a |
| GFS:P06147 | inositol polyphosphate-5-phosphatase F; Protien | Protien | n/a |
