Symbol: Name: ID: |
IVNS1ABP influenza virus NS1A binding protein GFS:6041 |
Gene name: | IVNS1ABP |
Chromosome: | 1q25.1-q31.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NS1-BP, HSPC068, NS-1, KIAA0850, ND1, KLHL39 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2152389 | Rat Genome Database ID: | RGD:1306290 |
HGNC ID: | HGNC:16951 | RefSeq IDs: | NM_006469 |
Entrez Gene ID: | 10625 | Ensembl Gene ID: | ENSG00000116679 |
VEGA IDs: | OTTHUMG00000035384 | UniProt ID: | Q9Y6Y0 |
UCSC ID: | uc001grl.2 | OMIM ID: | 609209 |
Pubmed: | PMID9696811 PMID 10048485 | ||
CCDS IDs: | CCDSCCDS1368.1 |
Influenza virus NS1A-binding protein is a protein that in humans is encoded by the IVNS1ABP gene.
Function: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
Products for IVNS1ABP gene
Catalog | Product Name | Application | Company |
GFS:E06041 | influenza virus NS1A binding protein; ELISA kit | ELISA | n/a |
GFS:A06041 | influenza virus NS1A binding protein; Anti | ANTIBODIES | n/a |
GFS:P06041 | influenza virus NS1A binding protein; Protien | Protien | n/a |