| Symbol: Name: ID: |
ICOSLG inducible T-cell co-stimulator ligand GFS:6181 |
| Gene name: | ICOSLG |
| Chromosome: | 21q22.3 |
| Previous Symbols: | ICOSL |
| Previous Names: | |
| Aliases: | KIAA0653, GL50, B7-H2, B7RP-1, B7H2, B7RP1, ICOS-L, CD275 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1354701 | Rat Genome Database ID: | RGD:1562791 |
| HGNC ID: | HGNC:17087 | RefSeq IDs: | NM_015259 |
| Entrez Gene ID: | 23308 | Ensembl Gene ID: | ENSG00000160223 |
| VEGA IDs: | OTTHUMG00000086920 | UniProt ID: | O75144 |
| UCSC ID: | uc002zee.2 | OMIM ID: | 605717 |
| Pubmed: | PMID9734811 PMID 11007762 | ||
| CCDS IDs: | CCDSCCDS42952.1 | ||
ICOS ligand is a protein that in humans is encoded by the ICOSLG gene. ICOSLG has also been designated as CD275 (cluster of differentiation 275).
Function: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
Products for ICOSLG gene
| Catalog | Product Name | Application | Company |
| GFS:E06181 | inducible T-cell co-stimulator ligand; ELISA kit | ELISA | n/a |
| GFS:A06181 | inducible T-cell co-stimulator ligand; Anti | ANTIBODIES | n/a |
| GFS:P06181 | inducible T-cell co-stimulator ligand; Protien | Protien | n/a |
