Symbol: Name: ID: |
HBXIP hepatitis B virus x interacting protein GFS:6854 |
Gene name: | HBXIP |
Chromosome: | 1p12 |
Previous Symbols: | |
Previous Names: | |
Aliases: | XIP, MGC71071 |
Name Aliases: | HBx-interacting protein, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1915826 | Rat Genome Database ID: | RGD:1305005 |
HGNC ID: | HGNC:17955 | RefSeq IDs: | NM_006402 |
Entrez Gene ID: | 10542 | Ensembl Gene ID: | ENSG00000134248 |
VEGA IDs: | OTTHUMG00000011568 | UniProt ID: | O43504 |
UCSC ID: | uc001dzr.2 | OMIM ID: | 608521 |
Pubmed: | PMID9499022 | ||
CCDS IDs: | CCDSCCDS824.1 |
Hepatitis B virus X-interacting protein is a protein that in humans is encoded by the HBXIP gene.
This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to alter the replication life cycle of the virus. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
Products for HBXIP gene
Catalog | Product Name | Application | Company |
GFS:E06854 | hepatitis B virus x interacting protein; ELISA kit | ELISA | n/a |
GFS:A06854 | hepatitis B virus x interacting protein; Anti | ANTIBODIES | n/a |
GFS:P06854 | hepatitis B virus x interacting protein; Protien | Protien | n/a |