Symbol: Name: ID: |
HCST hematopoietic cell signal transducer GFS:6065 |
Gene name: | HCST |
Chromosome: | 19q13.1 |
Previous Symbols: | PIK3AP |
Previous Names: | phosphoinositide-3-kinase adaptor protein |
Aliases: | DAP10, DKFZP586C1522, KAP10 |
Name Aliases: | DNAX-activation protein 10, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1344360 | Rat Genome Database ID: | RGD:1359238 |
HGNC ID: | HGNC:16977 | RefSeq IDs: | NM_001007469 |
Entrez Gene ID: | 10870 | Ensembl Gene ID: | ENSG00000126264 |
VEGA IDs: | OTTHUMG00000048132 | UniProt ID: | Q9UBK5 |
UCSC ID: | uc002ocl.1 | OMIM ID: | 604089 |
Pubmed: | PMID10426994 | ||
CCDS IDs: | CCDSCCDS32998.1 CCDS CCDS46057.1 |
Hematopoietic cell signal transducer is a protein that in humans is encoded by the HCST gene.
This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Products for HCST gene
Catalog | Product Name | Application | Company |
GFS:E06065 | hematopoietic cell signal transducer; ELISA kit | ELISA | n/a |
GFS:A06065 | hematopoietic cell signal transducer; Anti | ANTIBODIES | n/a |
GFS:P06065 | hematopoietic cell signal transducer; Protien | Protien | n/a |