Symbol: Name: ID: |
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 GFS:1825 |
Gene name: | HSP90B1 |
Chromosome: | 12q24.2-q24.3 |
Previous Symbols: | TRA1 |
Previous Names: | tumor rejection antigen (gp96) 1 |
Aliases: | GP96, GRP94 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98817 | Rat Genome Database ID: | RGD:1310482 |
HGNC ID: | HGNC:12028 | RefSeq IDs: | NM_003299 |
Entrez Gene ID: | 7184 | Ensembl Gene ID: | ENSG00000166598 |
VEGA IDs: | UniProt ID: | P14625 | |
UCSC ID: | uc001tkb.1 | OMIM ID: | 191175 |
Pubmed: | PMID16269234 | ||
CCDS IDs: | CCDSCCDS9094.1 |
Heat shock protein 90kDa beta member 1 (HSP90B1), known also as endoplasmin, gp96, grp94 and ERp99, is a chaperone protein that in humans is encoded by the HSP90B1 gene. HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Molecular chaperone that functions in the processing and transport of secreted proteins. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.
Products for HSP90B1 gene
Catalog | Product Name | Application | Company |
GFS:E01825 | heat shock protein 90kDa beta (Grp94), member 1; ELISA kit | ELISA | n/a |
GFS:A01825 | heat shock protein 90kDa beta (Grp94), member 1; Anti | ANTIBODIES | n/a |
GFS:P01825 | heat shock protein 90kDa beta (Grp94), member 1; Protien | Protien | n/a |