Symbol: Name: ID: |
GORASP1 golgi reassembly stacking protein 1, 65kDa GFS:5854 |
Gene name: | GORASP1 |
Chromosome: | 3p22-p21.33 |
Previous Symbols: | GOLPH5 |
Previous Names: | golgi phosphoprotein 5 |
Aliases: | GRASP65, P65, FLJ23443 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1921748 | Rat Genome Database ID: | RGD:621122 |
HGNC ID: | HGNC:16769 | RefSeq IDs: | NM_031899 |
Entrez Gene ID: | 64689 | Ensembl Gene ID: | ENSG00000114745 |
VEGA IDs: | OTTHUMG00000131292 | UniProt ID: | Q9BQQ3 |
UCSC ID: | uc003ciw.1 | OMIM ID: | 606867 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS2681.1 |
Golgi reassembly-stacking protein 1 is a protein that in humans is encoded by the GORASP1 gene.
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Several alternatively spliced transcript variants of this gene have been identified, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity: its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GM130, the docking of transport vesicles with the Golgi membranes.
Products for GORASP1 gene
Catalog | Product Name | Application | Company |
GFS:E05854 | golgi reassembly stacking protein 1, 65kDa; ELISA kit | ELISA | n/a |
GFS:A05854 | golgi reassembly stacking protein 1, 65kDa; Anti | ANTIBODIES | n/a |
GFS:P05854 | golgi reassembly stacking protein 1, 65kDa; Protien | Protien | n/a |