Symbol: Name: ID: |
GBA2 glucosidase, beta (bile acid) 2 GFS:7789 |
Gene name: | GBA2 |
Chromosome: | 9p13.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA1605, AD035, DKFZp762K054 |
Name Aliases: | bile acid beta-glucosidase, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2654325 | Rat Genome Database ID: | RGD:1305598 |
HGNC ID: | HGNC:18986 | RefSeq IDs: | NM_020944 |
Entrez Gene ID: | 57704 | Ensembl Gene ID: | ENSG00000070610 |
VEGA IDs: | OTTHUMG00000021024 | UniProt ID: | Q9HCG7 |
UCSC ID: | uc003zxw.2 | OMIM ID: | 609471 |
Pubmed: | PMID11489889 | ||
CCDS IDs: | CCDSCCDS6589.1 |
Non-lysosomal glucosylceramidase is an enzyme that in humans is encoded by the GBA2 gene.
This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism. [provided by RefSeq, Jul 2008].
Function: Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo.
Products for GBA2 gene
Catalog | Product Name | Application | Company |
GFS:E07789 | glucosidase, beta (bile acid) 2; ELISA kit | ELISA | n/a |
GFS:A07789 | glucosidase, beta (bile acid) 2; Anti | ANTIBODIES | n/a |
GFS:P07789 | glucosidase, beta (bile acid) 2; Protien | Protien | n/a |