Symbol: Name: ID: |
GHRL ghrelin/obestatin prepropeptide GFS:7018 |
Gene name: | GHRL |
Chromosome: | 3p26-p25 |
Previous Symbols: | |
Previous Names: | ghrelin, growth hormone secretagogue receptor ligand |
Aliases: | MTLRP, ghrelin, obestatin |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1930008 | Rat Genome Database ID: | RGD:632283 |
HGNC ID: | HGNC:18129 | RefSeq IDs: | NR_024134 |
Entrez Gene ID: | 51738 | Ensembl Gene ID: | ENSG00000157017 |
VEGA IDs: | OTTHUMG00000155360 | UniProt ID: | Q9UBU3 |
UCSC ID: | uc010hdj.2 | OMIM ID: | 605353 |
Pubmed: | PMID10930375 PMID 10604470 PMID 16284174 | ||
CCDS IDs: | CCDSCCDS33700.1 CCDS CCDS46747.1 CCDS CCDS46748.1 CCDS CCDS46749.1 CCDS CCDS46750.1 |
This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq, Oct 2008].
Products for GHRL gene
Catalog | Product Name | Application | Company |
GFS:E07018 | ghrelin/obestatin prepropeptide; ELISA kit | ELISA | n/a |
GFS:A07018 | ghrelin/obestatin prepropeptide; Anti | ANTIBODIES | n/a |
GFS:P07018 | ghrelin/obestatin prepropeptide; Protien | Protien | n/a |