Symbol: Name: ID: |
GEMIN4 gem (nuclear organelle) associated protein 4 GFS:4879 |
Gene name: | GEMIN4 |
Chromosome: | 17p13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HHRF-1, DKFZP434B131, p97, DKFZP434D174, HC56, HCAP1 |
Name Aliases: | HCC-associated protein 1, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2449313 | Rat Genome Database ID: | RGD:1563715 |
HGNC ID: | HGNC:15717 | RefSeq IDs: | NM_015721 |
Entrez Gene ID: | 50628 | Ensembl Gene ID: | ENSG00000179409 |
VEGA IDs: | UniProt ID: | P57678 | |
UCSC ID: | uc002frs.1 | OMIM ID: | 606969 |
Pubmed: | PMID10725331 | ||
CCDS IDs: | CCDSCCDS45559.1 |
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.
Products for GEMIN4 gene
Catalog | Product Name | Application | Company |
GFS:E04879 | gem (nuclear organelle) associated protein 4; ELISA kit | ELISA | n/a |
GFS:A04879 | gem (nuclear organelle) associated protein 4; Anti | ANTIBODIES | n/a |
GFS:P04879 | gem (nuclear organelle) associated protein 4; Protien | Protien | n/a |