Symbol: Name: ID: |
FHOD1 formin homology 2 domain containing 1 GFS:6805 |
Gene name: | FHOD1 |
Chromosome: | 16q22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FHOS |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2679008 | Rat Genome Database ID: | RGD:1589776 |
HGNC ID: | HGNC:17905 | RefSeq IDs: | NM_013241 |
Entrez Gene ID: | 29109 | Ensembl Gene ID: | ENSG00000135723 |
VEGA IDs: | OTTHUMG00000137521 | UniProt ID: | Q9Y613 |
UCSC ID: | uc002esl.2 | OMIM ID: | 606881 |
Pubmed: | PMID10352228 PMID 16112087 | ||
CCDS IDs: | CCDSCCDS10834.1 |
FH1/FH2 domain-containing protein 1 is a protein that in humans is encoded by the FHOD1 gene.
This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation.
Products for FHOD1 gene
Catalog | Product Name | Application | Company |
GFS:E06805 | formin homology 2 domain containing 1; ELISA kit | ELISA | n/a |
GFS:A06805 | formin homology 2 domain containing 1; Anti | ANTIBODIES | n/a |
GFS:P06805 | formin homology 2 domain containing 1; Protien | Protien | n/a |