Symbol: Name: ID: |
DYNLRB1 dynein, light chain, roadblock-type 1 GFS:4677 |
Gene name: | DYNLRB1 |
Chromosome: | 20q11.21 |
Previous Symbols: | DNCL2A |
Previous Names: | dynein, cytoplasmic, light polypeptide 2A |
Aliases: | DNLC2A, ROBLD1 |
Name Aliases: | roadblock domain containing 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1914318 | Rat Genome Database ID: | RGD:619910 |
HGNC ID: | HGNC:15468 | RefSeq IDs: | NM_014183 |
Entrez Gene ID: | 83658 | Ensembl Gene ID: | ENSG00000125971 |
VEGA IDs: | OTTHUMG00000032302 | UniProt ID: | Q9NP97 |
UCSC ID: | uc002xal.2 | OMIM ID: | 607167 |
Pubmed: | PMID11750132 PMID 16260502 | ||
CCDS IDs: | CCDSCCDS13235.1 |
Dynein light chain roadblock-type 1 is a protein that in humans is encoded by the DYNLRB1 gene.
This gene is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
Products for DYNLRB1 gene
Catalog | Product Name | Application | Company |
GFS:E04677 | dynein, light chain, roadblock-type 1; ELISA kit | ELISA | n/a |
GFS:A04677 | dynein, light chain, roadblock-type 1; Anti | ANTIBODIES | n/a |
GFS:P04677 | dynein, light chain, roadblock-type 1; Protien | Protien | n/a |