Symbol: Name: ID: |
DYNLL1 dynein, light chain, LC8-type 1 GFS:4685 |
Gene name: | DYNLL1 |
Chromosome: | 12q24.23 |
Previous Symbols: | DNCL1 |
Previous Names: | dynein, cytoplasmic, light polypeptide 1 |
Aliases: | hdlc1, DLC1, PIN, LC8, DLC8 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1861457 | Rat Genome Database ID: | RGD:619866 |
HGNC ID: | HGNC:15476 | RefSeq IDs: | NM_001037494 |
Entrez Gene ID: | 8655 | Ensembl Gene ID: | ENSG00000088986 |
VEGA IDs: | UniProt ID: | P63167 | |
UCSC ID: | uc001tym.2 | OMIM ID: | 601562 |
Pubmed: | PMID8628263 PMID 8864115 PMID 16260502 | ||
CCDS IDs: | CCDSCCDS9200.1 |
Dynein light chain 1, cytoplasmic is a protein that in humans is encoded by the DYNLL1 gene.
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008].
Products for DYNLL1 gene
Catalog | Product Name | Application | Company |
GFS:E04685 | dynein, light chain, LC8-type 1; ELISA kit | ELISA | n/a |
GFS:A04685 | dynein, light chain, LC8-type 1; Anti | ANTIBODIES | n/a |
GFS:P04685 | dynein, light chain, LC8-type 1; Protien | Protien | n/a |