Symbol: Name: ID: |
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 GFS:7580 |
Gene name: | DYNC1LI1 |
Chromosome: | 3p23 |
Previous Symbols: | DNCLI1 |
Previous Names: | dynein, cytoplasmic, light intermediate polypeptide 1 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2135610 | Rat Genome Database ID: | RGD:71072 |
HGNC ID: | HGNC:18745 | RefSeq IDs: | NM_016141 |
Entrez Gene ID: | 51143 | Ensembl Gene ID: | ENSG00000144635 |
VEGA IDs: | OTTHUMG00000130750 | UniProt ID: | Q9Y6G9 |
UCSC ID: | uc003cfb.3 | OMIM ID: | |
Pubmed: | PMID16260502 | ||
CCDS IDs: | CCDSCCDS2654.1 |
Cytoplasmic dynein 1 light intermediate chain 1 is a protein that in humans is encoded by the DYNC1LI1 gene.
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
Products for DYNC1LI1 gene
Catalog | Product Name | Application | Company |
GFS:E07580 | dynein, cytoplasmic 1, light intermediate chain 1; ELISA kit | ELISA | n/a |
GFS:A07580 | dynein, cytoplasmic 1, light intermediate chain 1; Anti | ANTIBODIES | n/a |
GFS:P07580 | dynein, cytoplasmic 1, light intermediate chain 1; Protien | Protien | n/a |