Symbol: Name: ID: |
DIAPH3 diaphanous homolog 3 (Drosophila) GFS:4689 |
Gene name: | DIAPH3 |
Chromosome: | 13q21.2 |
Previous Symbols: | |
Previous Names: | diaphanous (Drosophila, homolog) 3 |
Aliases: | DRF3, FLJ34705 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1927222 | Rat Genome Database ID: | RGD:1593287 |
HGNC ID: | HGNC:15480 | RefSeq IDs: | NM_001042517 |
Entrez Gene ID: | 81624 | Ensembl Gene ID: | ENSG00000139734 |
VEGA IDs: | OTTHUMG00000017004 | UniProt ID: | Q9NSV4 |
UCSC ID: | uc001vht.2 | OMIM ID: | |
Pubmed: | PMID14767582 | ||
CCDS IDs: | CCDSCCDS41898.1 |
Function: Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).
Products for DIAPH3 gene
Catalog | Product Name | Application | Company |
GFS:E04689 | diaphanous homolog 3 (Drosophila); ELISA kit | ELISA | n/a |
GFS:A04689 | diaphanous homolog 3 (Drosophila); Anti | ANTIBODIES | n/a |
GFS:P04689 | diaphanous homolog 3 (Drosophila); Protien | Protien | n/a |