Symbol: Name: ID: |
DEGS1 degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) GFS:3219 |
Gene name: | DEGS1 |
Chromosome: | 1q41-q42.12 |
Previous Symbols: | DEGS |
Previous Names: | degenerative spermatocyte homolog, lipid desaturase (Drosophila) |
Aliases: | MLD, Des-1, DES1, FADS7 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1097711 | Rat Genome Database ID: | RGD:70917 |
HGNC ID: | HGNC:13709 | RefSeq IDs: | NM_003676 |
Entrez Gene ID: | 8560 | Ensembl Gene ID: | ENSG00000143753 |
VEGA IDs: | OTTHUMG00000037496 | UniProt ID: | O15121 |
UCSC ID: | uc001hoj.2 | OMIM ID: | |
Pubmed: | PMID9188692 | ||
CCDS IDs: | CCDSCCDS1540.1 |
This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010].
Function: Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine).
Products for DEGS1 gene
Catalog | Product Name | Application | Company |
GFS:E03219 | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila); ELISA kit | ELISA | n/a |
GFS:A03219 | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila); Anti | ANTIBODIES | n/a |
GFS:P03219 | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila); Protien | Protien | n/a |