| Symbol: Name: ID: |
DEFB105A defensin, beta 105A GFS:6977 |
| Gene name: | DEFB105A |
| Chromosome: | 8p23.1 |
| Previous Symbols: | DEFB105 |
| Previous Names: | defensin, beta 105 |
| Aliases: | DEFB-5 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1924924 | Rat Genome Database ID: | RGD:1564879 |
| HGNC ID: | HGNC:18087 | RefSeq IDs: | NM_152250 |
| Entrez Gene ID: | 245908 | Ensembl Gene ID: | ENSG00000186562 |
| VEGA IDs: | OTTHUMG00000150011 | UniProt ID: | Q8NG35 |
| UCSC ID: | uc011kwp.1 | OMIM ID: | |
| Pubmed: | PMID11854508 PMID 12734011 | ||
| CCDS IDs: | CCDSCCDS34832.1 | ||
Beta-defensin 105 is a protein that in humans is encoded by the DEFB105A gene.
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105A, represents the more centromeric copy. [provided by RefSeq, Jul 2008].
Function: Has antibacterial activity (Potential).
Products for DEFB105A gene
| Catalog | Product Name | Application | Company |
| GFS:E06977 | defensin, beta 105A; ELISA kit | ELISA | n/a |
| GFS:A06977 | defensin, beta 105A; Anti | ANTIBODIES | n/a |
| GFS:P06977 | defensin, beta 105A; Protien | Protien | n/a |
