Symbol: Name: ID: |
DBR1 debranching enzyme homolog 1 (S. cerevisiae) GFS:4790 |
Gene name: | DBR1 |
Chromosome: | 3q22.3 |
Previous Symbols: | |
Previous Names: | debranching enzyme (S. Cerevisiae) homolog 1 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1931520 | Rat Genome Database ID: | RGD:1598038 |
HGNC ID: | HGNC:15594 | RefSeq IDs: | NM_016216 |
Entrez Gene ID: | 51163 | Ensembl Gene ID: | ENSG00000138231 |
VEGA IDs: | OTTHUMG00000159824 | UniProt ID: | Q9UK59 |
UCSC ID: | uc003erv.2 | OMIM ID: | 607024 |
Pubmed: | PMID10982890 | ||
CCDS IDs: | CCDSCCDS33863.1 |
Lariat debranching enzyme is a protein that in humans is encoded by the DBR1 gene.
The RNA lariat debranching enzyme, or DBR1, specifically hydrolyzes 2-prime-to-5-prime branched phosphodiester bonds at the branch point of excised lariat intron RNA and converts them into linear molecules.[supplied by OMIM, Jul 2002].
Function: Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via a RNA lariat intermediate in cDNA synthesis.
Products for DBR1 gene
Catalog | Product Name | Application | Company |
GFS:E04790 | debranching enzyme homolog 1 (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A04790 | debranching enzyme homolog 1 (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P04790 | debranching enzyme homolog 1 (S. cerevisiae); Protien | Protien | n/a |