Symbol: Name: ID: |
CLASP2 cytoplasmic linker associated protein 2 GFS:6171 |
Gene name: | CLASP2 |
Chromosome: | 3p24.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0627 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1923749 | Rat Genome Database ID: | RGD:619789 |
HGNC ID: | HGNC:17078 | RefSeq IDs: | NM_015097 |
Entrez Gene ID: | 23122 | Ensembl Gene ID: | ENSG00000163539 |
VEGA IDs: | OTTHUMG00000156489 | UniProt ID: | O75122 |
UCSC ID: | uc003cfu.2 | OMIM ID: | 605853 |
Pubmed: | PMID9734811 PMID 10899121 | ||
CCDS IDs: |
Cytoplasmic linker associated protein 2, also known as CLASP2, is a protein which in humans is encoded by the CLASP2 gene.
Function: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Products for CLASP2 gene
Catalog | Product Name | Application | Company |
GFS:E06171 | cytoplasmic linker associated protein 2; ELISA kit | ELISA | n/a |
GFS:A06171 | cytoplasmic linker associated protein 2; Anti | ANTIBODIES | n/a |
GFS:P06171 | cytoplasmic linker associated protein 2; Protien | Protien | n/a |