| Symbol: Name: ID: |
CLNK cytokine-dependent hematopoietic cell linker GFS:6490 |
| Gene name: | CLNK |
| Chromosome: | 4p16.1 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | MIST |
| Name Aliases: | mast cell immunoreceptor signal transducer |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1351468 | Rat Genome Database ID: | RGD:1562417 |
| HGNC ID: | HGNC:17438 | RefSeq IDs: | NM_052964 |
| Entrez Gene ID: | 116449 | Ensembl Gene ID: | ENSG00000109684 |
| VEGA IDs: | UniProt ID: | Q7Z7G1 | |
| UCSC ID: | uc003gmo.3 | OMIM ID: | 611434 |
| Pubmed: | PMID10562326 PMID 10744659 | ||
| CCDS IDs: | CCDSCCDS47024.1 | ||
MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM, Mar 2008].
Function: Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT (By similarity).
Products for CLNK gene
| Catalog | Product Name | Application | Company |
| GFS:E06490 | cytokine-dependent hematopoietic cell linker; ELISA kit | ELISA | n/a |
| GFS:A06490 | cytokine-dependent hematopoietic cell linker; Anti | ANTIBODIES | n/a |
| GFS:P06490 | cytokine-dependent hematopoietic cell linker; Protien | Protien | n/a |
