Symbol: Name: ID: |
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase GFS:7163 |
Gene name: | CMAS |
Chromosome: | 12p12.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | CMP-Neu5Ac synthetase |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1337124 | Rat Genome Database ID: | RGD:1310911 |
HGNC ID: | HGNC:18290 | RefSeq IDs: | NM_018686 |
Entrez Gene ID: | 55907 | Ensembl Gene ID: | ENSG00000111726 |
VEGA IDs: | UniProt ID: | Q8NFW8 | |
UCSC ID: | uc001rfm.2 | OMIM ID: | 603316 |
Pubmed: | PMID8889549 PMID 7566098 | ||
CCDS IDs: | CCDSCCDS8696.1 |
N-acylneuraminate cytidylyltransferase is an enzyme that in humans is encoded by the CMAS gene.
The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus. [provided by RefSeq, Jul 2008].
Function: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
Products for CMAS gene
Catalog | Product Name | Application | Company |
GFS:E07163 | cytidine monophosphate N-acetylneuraminic acid synthetase; ELISA kit | ELISA | n/a |
GFS:A07163 | cytidine monophosphate N-acetylneuraminic acid synthetase; Anti | ANTIBODIES | n/a |
GFS:P07163 | cytidine monophosphate N-acetylneuraminic acid synthetase; Protien | Protien | n/a |