Symbol: Name: ID: |
CDA cytidine deaminase GFS:6212 |
Gene name: | CDA |
Chromosome: | 1p36.2-p35 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CDD |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919519 | Rat Genome Database ID: | RGD:1311101 |
HGNC ID: | HGNC:1712 | RefSeq IDs: | NM_001785 |
Entrez Gene ID: | 978 | Ensembl Gene ID: | ENSG00000158825 |
VEGA IDs: | OTTHUMG00000002845 | UniProt ID: | P32320 |
UCSC ID: | uc001bdk.2 | OMIM ID: | 123920 |
Pubmed: | PMID8422236 PMID 9878810 | ||
CCDS IDs: | CCDSCCDS210.1 |
Cytidine deaminase is an enzyme that in humans is encoded by the CDA gene.
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
Products for CDA gene
Catalog | Product Name | Application | Company |
GFS:E06212 | cytidine deaminase; ELISA kit | ELISA | n/a |
GFS:A06212 | cytidine deaminase; Anti | ANTIBODIES | n/a |
GFS:P06212 | cytidine deaminase; Protien | Protien | n/a |